The influence of polyinosinic-polycytidylic acid complex on vaccinia keratitis in rabbits.

0,cular complications after smallpox vaccination are rare occurrences, but still may cause considerable morbidity. In some of the developing countries, vaccinia keratitis is still an important cause of blindness. Keratitis is the most serious ocular problem and occurs in about 20 to 30 per cent of ocular vaccinia. A diverse number of therapeutic regimes have been used in the treatment of ocular vaccinia, including vaccinia antiserum, xray therapy, gamma globulin, antibiotics, and cytosine arabinoside, with essentially